Thursday, 11 August 2011

TENORMIN (atenolol)

TENORMIN® (atenolol), a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]-. The molecular and structural formulas are:
TENORMIN® (atenolol) structural formula illustration

C14H22N2O3
Atenolol (free base) has a molecular weight of 266. It is a relatively polar hydrophilic compound with a water solubility of 26.5 mg/ mL at 37°C and a log partition coefficient (octanol/water) of 0.23. It is freely soluble in 1N HCl (300 mg/mL at 25°C) and less soluble in chloroform (3 mg/mL at 25°C).
TENORMIN (atenolol tablets) is available as 25, 50 and 100 mg tablets for oral administration.
Inactive Ingredients: Magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate.

HEPADIAL Biocodex/Hllton

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Drug Category: Choleretic agent.

Generic Name: Dimecrotic acid.

Contents: Tabs: Dimecrotic acid 50mg (magne­sium salt).

Indications: Hepato digestive insufficiency and its manifestations (Dyspepsia, nausea, hedache of digestive organs). Food intoxication, biliary dyski-nesia. Sequelae of viral hepatitis. Constipation. Post-chiolecystectomy. Hepatic protection of alco­holics.

Dosage: Adults: 3 or 4 tabs daily, to be swallowed at meal time.  Children: Not recommended.

Contra-Ind: Bile duct obstruction and severe hepa-tocellular failure.

MODIUM Janssen-Cilag

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Drug Category: Opiate

Generic Name: Loperamide HCI.

Contents: Caps: Loperamide HCI 2mg.

Indications: Diarrhoea.

Dosage: Adults: Acute diarrhoea: initially 2 caps, then 1 at each loose stool (usually 3-4 daily). Max, 8 daily.

Chronic diarrhoea: initially 2-4 caps, daily in divided doses.

Children: Acute diarrhoea: 9-12 years, 1 cap four times daily.

Precautions: Severe acute ulcerative colitis.

Adverse effects: Rashes.

LANSOR Pharmedic

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Drug Category: Proton pump inhibitor
Generic Name: Lansoprazole.
Contents: Caps: Lansoprazole 30mg.

RISEK Getz Pharma

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Drug Category: Proton pump inhibitor.

Generic Name: Omeprazole.

Contents: Caps: Omeprazole 20mg.
Infusion: Per Vial: Omeprazole sodium 42.6mg equivalent to omeprazole 40mg.

Monday, 8 August 2011

QALSAN Novartis

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Drug Category: Calcium supplement.

Generic Name: Calcium carbonate.

Contents: Chewable Tabs: Cacium carbonate USP 1250mg (500mg elemental calcium); sugar free (contains aspartame).

Indications: Raised calcium requirements, e.g. during pregnancy, lactation, children and adoles­cents at times of rapid growth. Inadequate intake of calcium in diet. Osteoporosis. As a supplement to vit D in treatment of rickets and osteomalacia. Latent tetany.

Dosage: Adults & Children: As a supplement to diet 1 tab daily. The dosage may be increased when there is higher demand for calcium e.g. pregnancy, lactation etc.

Contra-ind: Hypercalcaemia, hypercalciuria, se­vere renal failure, renal calculi, galactosaemia.

Precautions: In renal impairment, electrolyte imbal­ance, monitor blood and urinary calcium levels.

Interactions: Cardiac glycosides (inj. only), thia-zides, tetracyclines.

Adverse effects: Diarrhoea.

NAVIDOXINE

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Drug Category: Antiemetic(piperazine deriva-tive)/vitamin.
Contents: Tabs: Meclizine 2HCI 25mg, vit B6 50mg.
Indications: Prophylaxis and treatment of nausea and vomiting in pregnancy.
Dosage: Adults: Once a day 1 or 2 tabs at bed­time.